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In a villa in the heart of Lima, a baby girl is born. Her name is Isabel, but her natural beauty quickly earns her the nickname of one of the loveliest flowers, Rose. From a young age, Rose isn't interested in suitors or marriage. She wants to enter religious life in a convent, but when her family refuses to let her go, Rose must turn to God to help her overcome obstacles hindering her from blooming into the person He wants her to be. Petal by petal, God's plan unfolds for the first Saint of the Americas.